Automated Plasmid Minipreps with the Opentrons Flex® Automated Vacuum Module Application Note

Plasmid DNA miniprep purification is a routine but labor-intensive step in molecular biology workflows, typically relying on manual vacuum manifolds or centrifugation to process silica-membrane spin columns in tubes or plates. As sample throughput increases, manual processing becomes a bottleneck and a source of errors and run-to-run variability

The Opentrons Flex paired with the Flex Automated Vacuum Module enables full automation of the miniprep workflow starting with E. coli cell pellets and finishing with eluted plasmid DNA without operator intervention

Learn how this approach reduces hands-on time, ensures user-to-user consistency, and scales cleanly from small validation runs to highthroughput plasmid preparation by downloading the application note today.